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Proceedings Paper

Cochlear anatomy using micro computed tomography (micro CT) imaging
Author(s): Namkeun Kim; Yongjin Yoon; Charles Steele; Sunil Puria
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Paper Abstract

A novel micro computed tomography (μCT) image processing method was implemented to measure anatomical features of the gerbil and chinchilla cochleas, taking into account the bent modailosis axis. Measurements were made of the scala vestibule (SV) area, the scala tympani (SV) area, and the basilar membrane (BM) width using prepared cadaveric temporal bones. 3-D cochlear structures were obtained from the scanned images using a process described in this study. It was necessary to consider the sharp curvature of mododailosis axis near the basal region. The SV and ST areas were calculated from the μCT reconstructions and compared with existing data obtained by Magnetic Resonance Microscopy (MRM), showing both qualitative and quantitative agreement. In addition to this, the width of the BM, which is the distance between the primary and secondary osseous spiral laminae, is calculated for the two animals and compared with previous data from the MRM method. For the gerbil cochlea, which does not have much cartilage in the osseous spiral lamina, the μCT-based BM width measurements show good agreement with previous data. The chinchilla BM, which contains more cartilage in the osseous spiral lamina than the gerbil, shows a large difference in the BM widths between the μCT and MRM methods. The SV area, ST area, and BM width measurements from this study can be used in building an anatomically based mathematical cochlear model.

Paper Details

Date Published: 8 February 2008
PDF: 10 pages
Proc. SPIE 6842, Photonic Therapeutics and Diagnostics IV, 68421A (8 February 2008); doi: 10.1117/12.774349
Show Author Affiliations
Namkeun Kim, Stanford Univ. (United States)
Veterans Affairs (United States)
Yongjin Yoon, Stanford Univ. (United States)
Charles Steele, Stanford Univ. (United States)
Sunil Puria, Stanford Univ. (United States)
Veterans Affairs (United States)

Published in SPIE Proceedings Vol. 6842:
Photonic Therapeutics and Diagnostics IV
Kenton W. Gregory M.D.; Reza S. Malek M.D.; Nikiforos Kollias; Brian Jet-Fei Wong M.D.; Henry Hirschberg M.D.; Justus F. R. Ilgner M.D.; Steen J. Madsen; Guillermo J. Tearney M.D.; Bernard Choi; Haishan Zeng, Editor(s)

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