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Proceedings Paper

Expectation maximization SPECT reconstruction with a content-adaptive singularity-based mesh-domain image model
Author(s): Yao Lu; Hongwei Ye; Yuesheng Xu; Xiaofei Hu; Levon Vogelsang; Lixin Shen; David Feiglin; Edward Lipson; Andrzej Krol
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Paper Abstract

To improve the speed and quality of ordered-subsets expectation-maximization (OSEM) SPECT reconstruction, we have implemented a content-adaptive, singularity-based, mesh-domain, image model (CASMIM) with an accurate algorithm for estimation of the mesh-domain system matrix. A preliminary image, used to initialize CASMIM reconstruction, was obtained using pixel-domain OSEM. The mesh-domain representation of the image was produced by a 2D wavelet transform followed by Delaunay triangulation to obtain joint estimation of nodal locations and their activity values. A system matrix with attenuation compensation was investigated. Digital chest phantom SPECT was simulated and reconstructed. The quality of images reconstructed with OSEM-CASMIM is comparable to that from pixel-domain OSEM, but images are obtained five times faster by the CASMIM method.

Paper Details

Date Published: 18 March 2008
PDF: 6 pages
Proc. SPIE 6913, Medical Imaging 2008: Physics of Medical Imaging, 69132F (18 March 2008); doi: 10.1117/12.773082
Show Author Affiliations
Yao Lu, Syracuse Univ. (United States)
Hongwei Ye, Syracuse Univ. (United States)
Yuesheng Xu, Syracuse Univ. (United States)
Xiaofei Hu, Syracuse Univ. (United States)
Levon Vogelsang, Syracuse Univ. (United States)
Lixin Shen, Syracuse Univ. (United States)
David Feiglin, SUNY Upstate Medical Univ. (United States)
Syracuse Univ. (United States)
Edward Lipson, Syracuse Univ. (United States)
SUNY Upstate Medical Univ. (United States)
Andrzej Krol, SUNY Upstate Medical Univ. (United States)
Syracuse Univ. (United States)

Published in SPIE Proceedings Vol. 6913:
Medical Imaging 2008: Physics of Medical Imaging
Jiang Hsieh; Ehsan Samei, Editor(s)

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