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Proceedings Paper

White matter tractographies registration using Gaussian mixture modeling
Author(s): Orly Zvitia; Arnaldo Mayer; Hayit Greenspan
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Paper Abstract

This paper proposes a novel and robust approach to the registration (matching) of intra-subject white matter (WM) fiber sets extracted from DT-MRI scans by Tractography. For each fiber, a feature space representation is obtained by appending the sequence of its 3D coordinates. Clustering by non-parametric adaptive mean shift provides a representative fiber for each cluster hereafter termed the fiber-mode (FM). For each FM, the parameters of a multivariate Gaussian are computed from its fiber population, leading to a mixture of Gaussians (MoG) for the whole fiber set. The number of Gaussians used for a fiber set equals the number of FM representing the set. The alignment of two fiber sets is then treated as the alignment between two MoGs, and is solved by maximizing the correlation ratio between them. Initial results are presented for real intrasubject fiber sets and synthetic transformations.

Paper Details

Date Published: 19 March 2008
PDF: 9 pages
Proc. SPIE 6914, Medical Imaging 2008: Image Processing, 69142G (19 March 2008); doi: 10.1117/12.769809
Show Author Affiliations
Orly Zvitia, Tel Aviv Univ. (Israel)
Arnaldo Mayer, Tel Aviv Univ. (Israel)
Hayit Greenspan, Tel Aviv Univ. (Israel)

Published in SPIE Proceedings Vol. 6914:
Medical Imaging 2008: Image Processing
Joseph M. Reinhardt; Josien P. W. Pluim, Editor(s)

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