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Proceedings Paper

Image-based investigation of hemodynamics and rupture of cerebral aneurysms of a single morphological type: terminal aneurysms
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Paper Abstract

In this study, the relationship between hemodynamics patterns and aneurysmal rupture was investigated in cerebral aneurysms of a single morphological type (terminal aneurysms) regardless of their location. Hemodynamics information (intra-aneurysmal velocity and pressure fields and wall shear stress distributions) was derived from image-based computational fluid dynamics models with realistic patient specific anatomies. A total of 41 patient-specific models constructed from 3D rotational angiography images were analyzed. The results suggest that high wall shear stress may be associated with aneurysm rupture and that in turn different flow splitting patterns from the parent artery to the daughter branches and the aneurysm produce different levels of wall shear stress.

Paper Details

Date Published: 12 March 2008
PDF: 9 pages
Proc. SPIE 6916, Medical Imaging 2008: Physiology, Function, and Structure from Medical Images, 69160K (12 March 2008); doi: 10.1117/12.769239
Show Author Affiliations
Marcelo Castro, George Mason Univ. (United States)
Christopher Putman, Inova Fairfax Hospital (United States)
Alessandro Radaelli, Univ. Pompeu Fabra (Spain)
Alejandro Frangi, Univ. Pompeu Fabra (Spain)
Juan Cebral, George Mason Univ. (United States)

Published in SPIE Proceedings Vol. 6916:
Medical Imaging 2008: Physiology, Function, and Structure from Medical Images
Xiaoping P. Hu; Anne V. Clough, Editor(s)

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