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Proceedings Paper

Multiphoton autofluorescence and second-harmonic generation diagnosis of hepatocellular carcinoma
Author(s): Yuan Liu; Tzu-Lin Sun; Chuen-Huei Yang; Vladimir A. Hovhannisyan; Wei-Chou Lin; Hsuan-Shu Lee; Chen-Yuan Dong
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Paper Abstract

By using two-photon autofluorescence (TPAF) and second harmonics generation (SHG), we imaged hepatocellular carcinoma (HCC) biopsies from the human patients and compared them with the conventional histological biopsies. We found that multiphoton microscopy may be used to obtain label-free images of liver tissues and may be developed into an effective diagnostic tool for liver diseases.

Paper Details

Date Published: 14 March 2008
PDF: 5 pages
Proc. SPIE 6863, Optical Diagnostics and Sensing VIII, 68630J (14 March 2008); doi: 10.1117/12.764276
Show Author Affiliations
Yuan Liu, National Taiwan Univ. (Taiwan)
Tzu-Lin Sun, National Taiwan Univ. (Taiwan)
Chuen-Huei Yang, National Taiwan Univ. (Taiwan)
Vladimir A. Hovhannisyan, National Taiwan Univ. (Taiwan)
Wei-Chou Lin, National Taiwan Univ. Hospital (Taiwan)
Hsuan-Shu Lee, National Taiwan Univ. Hospital (Taiwan)
Chen-Yuan Dong, National Taiwan Univ. (Taiwan)

Published in SPIE Proceedings Vol. 6863:
Optical Diagnostics and Sensing VIII
Gerard L. Coté; Alexander V. Priezzhev, Editor(s)

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