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Proceedings Paper

Peptide targeting of quantum dots to human breast cancer cells
Author(s): Emily M. Haglund; Mary-Margaret Seale-Goldsmith; Deepika Dhawan; Jane Stewart; Jose Ramos-Vara; Christy L. Cooper; Lisa M. Reece; Timothy Husk; Donald Bergstrom; Deborah Knapp; James F. Leary
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Paper Abstract

Nanomedical approaches to diseases such as cancer provide great promise with respect to diagnostic and therapeutic applications. The impact of nanomedicine versus conventional therapies will be realized with regard to their specific cell targeting capabilities. Semiconductor nanoparticles have distinct advantages due to their chemical conjugation and detection characteristics. The attachment of a peptide sequence, LTVSPWY, was completed. These nanoparticles successfully targeted in vitro and in vivo systems. This technology can be utilized as a base mechanism for the construction of a multifunctional nanomedical system. Nanomedicine has great potential for impacting the treatment of specific diseases and healthcare delivery methods.

Paper Details

Date Published: 13 March 2008
PDF: 8 pages
Proc. SPIE 6866, Colloidal Quantum Dots for Biomedical Applications III, 68660S (13 March 2008); doi: 10.1117/12.764107
Show Author Affiliations
Emily M. Haglund, Purdue Univ. (United States)
Mary-Margaret Seale-Goldsmith, Purdue Univ. (United States)
Deepika Dhawan, Purdue Univ. (United States)
Jane Stewart, Purdue Univ. (United States)
Jose Ramos-Vara, Purdue Univ. (United States)
Christy L. Cooper, Purdue Univ. (United States)
Lisa M. Reece, Purdue Univ. (United States)
Timothy Husk, Purdue Univ. (United States)
Donald Bergstrom, Purdue Univ. (United States)
Deborah Knapp, Purdue Univ. (United States)
James F. Leary, Purdue Univ. (United States)

Published in SPIE Proceedings Vol. 6866:
Colloidal Quantum Dots for Biomedical Applications III
Marek Osinski; Thomas M. Jovin; Kenji Yamamoto, Editor(s)

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