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Proceedings Paper

Autofluorescence spectroscopic imaging for laryngeal cancer detection
Author(s): Lin Kan; Wei Zheng; Zhiwei Huang
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Paper Abstract

Autofluorescence imaging has shown a high sensitivity for early diagnosis and detection of cancer and precancer in humans, however, this diagnostic technique has a limitation with high false positive rates resulting in a low diagnostic specificity. In this study, we develop an endoscope-based autofluorescence imaging system in combination with spectroscopy measurement system for tissue diagnostics and characterization in the head and neck. The results show that combining the spectroscopy and imaging techniques can improve both the diagnostic sensitivity and specificity for discriminating laryngeal carcinoma from normal tissue.

Paper Details

Date Published: 12 February 2008
PDF: 4 pages
Proc. SPIE 6848, Advanced Biomedical and Clinical Diagnostic Systems VI, 68480G (12 February 2008); doi: 10.1117/12.762249
Show Author Affiliations
Lin Kan, National Univ. of Singapore (Singapore)
Wei Zheng, National Univ. of Singapore (Singapore)
Zhiwei Huang, National Univ. of Singapore (Singapore)

Published in SPIE Proceedings Vol. 6848:
Advanced Biomedical and Clinical Diagnostic Systems VI
Tuan Vo-Dinh; Warren S. Grundfest; David A. Benaron; Gerald E. Cohn, Editor(s)

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