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Proceedings Paper

Surface enhanced Raman spectroscopy on chip
Author(s): Jorg Hubner; Thomas Anhøj; Sarah Pedersen; Dan A. Zauner; Anders M. Jorgensen; Gabriella Blagoi; Ivan Talian; Ole Hansen
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Paper Abstract

In this paper we report on an integrated spectrometer device, fabricated in epoxy resist (SU-8) on silicon, designed for Raman spectroscopy and direct coupling to a CCD element. Furthermore a nanostructured surface is prepared on a gold coated silicon chip to enhance the Raman signal. We show examples of low resolution Surface Enhanced Raman Spectra (SERS) recorded with this chip and provide an outlook on the future possibilities. Traditional optical detection in Lab-on-Chip devices often requires sample pretreatment including chemical reactions in order to identify and detect a certain substance (e.g. attachment of a fluorescent marker). The basic idea in bringing Raman spectroscopy to the chip is to avoid these chemical reactions and directly enable identification of the substance by its Raman spectrum. Two different methods were used to prepare the nanostructured surfaces. The first method is based on an aqueous suspension of gold nanoparticles and polystyrene beads deposited on a gold surface. The suspension was dried and the polystyrene beads were removed using an appropriate solvent (methane dichloride). The second approach includes gold coated random silicon nanostructures so-called "black silicon". The surfaces were characterized using a commercial Raman spectrometer and the enhancement factor was found to be strongly dependant on the concentration on the sample surface. The surface was impregnated with a droplet (10 μl, 100 μM) of Rhodamin 6G and Nileblue respectively. Using the on-chip spectrometer we have recorded surface enhanced Raman spectra of Nileblue and Rhodamin 6G respectively. The results show that these systems are suitable for low cost extremely compact Raman sensors with possible applications reaching from process monitoring to homeland security and point of care devices.

Paper Details

Date Published: 28 February 2008
PDF: 10 pages
Proc. SPIE 6896, Integrated Optics: Devices, Materials, and Technologies XII, 689614 (28 February 2008); doi: 10.1117/12.761076
Show Author Affiliations
Jorg Hubner, Technical Univ. of Denmark (Denmark)
Thomas Anhøj, Technical Univ. of Denmark (Denmark)
Sarah Pedersen, Technical Univ. of Denmark (Denmark)
Dan A. Zauner, Technical Univ. of Denmark (Denmark)
Anders M. Jorgensen, Technical Univ. of Denmark (Denmark)
Gabriella Blagoi, Technical Univ. of Denmark (Denmark)
Ivan Talian, P.J. Šafárik Univ. (Slovak Republic)
Ole Hansen, Technical Univ. of Denmark (Denmark)

Published in SPIE Proceedings Vol. 6896:
Integrated Optics: Devices, Materials, and Technologies XII
Christoph M. Greiner; Christoph A. Waechter, Editor(s)

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