Optical coherence tomography(OCT) is a new non-invasive, cross-sectional imaging technique that measures depth resolved reflectance of tissue by employing low-coherence interferometer. The acquisition of the signal may be achieved either in the time domain(TD) by altering the reference arm length of the interferometer, or in the frequency domain(FD) where the individual spectral frequency components of the interference signal are acquired.In this paper, the principle of FD OCT is presented and the main parameters which influence the quality of image are discussed in theory. A spectral domain OCT(SDOCT) system is introduced which can avoid scanning of the reference thus can reach very high acquisition speed. A design which combines the SOCT technique and endoscopy is put forward. We propose possible solutions to minimize the structure of rotating scanning which uses min-ultrasonic-motor to drive reflecting prism according to alimentary tract endoscopy's feature. Multi-layer cover-glasses (the thickness of every layer is 260.0μm) and onion-skin (1mm thick) are used as the object for imaging to prove that the system is successful. The lateral resolution is 15μm and the measuring range is 4.5mm. We obtain he measuring distance of two glass layers and the depth scan of an onion from the surface.

Date Published: 8 January 2008
PDF: 10 pages
Proc. SPIE 6826, Optics in Health Care and Biomedical Optics III, 682607 (8 January 2008); doi: 10.1117/12.755761

Published in SPIE Proceedings Vol. 6826:
Optics in Health Care and Biomedical Optics III
Xingde Li; Qingming Luo; Ying Gu M.D., Editor(s)