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Proceedings Paper

Study and realization of real-time in-depth dosimetry system for IORT (intra operative radiation therapy)
Author(s): R. Brancaccio; M. Bettuzzi; F. Casali; M. P. Morigi; A. Berdondini; C. Bruno; Y. F. Tchuente Siaka; A. Santaniello; E. Lamanna; A. S. Fiorillo; G. Barca; F. Castrovillari
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Paper Abstract

Intra Operative Radiation Therapy (IORT) is a technique based on delivery of a high dose of ionising radiation to the cancer tissue, after tumour ablation, during surgery, while reducing the exposure of normal surrounding tissue. Novac7 and Liac are new linear accelerators expressly conceived to perform in the operating room. These accelerators supply electron beams with high dose rate. Because of this peculiar characteristic, classical dosimetric techniques are not able to give at once a real-time response and an extensive measure of the absorbed dose. In past years the authors realized a prototype for IORT dosimetry able to give the real time bi-dimensional image of dose distribution on a single layer. In the framework of a research project funded by the INFN (Italian National Institute of Nuclear Physics), a collaboration between the Physics Department of Bologna, Italy, the Physics Department of Cosenza and the Medicine Department of Catanzaro, Italy, has studied a new system composed of six layers. Each layer includes two orthogonal bundles of scintillating optical fibres. The fibres are optically coupled with four arrays of photodiodes as read-out system. This new system will be able to characterize completely the electron beam in energy, intensity and spatial distribution. In real time it will be able to measure the 3D dose distribution, providing a full check of quality assurance for IORT. The various phases of design, development and characterization of the instrument will be illustrated, as well as some experimental tests performed with the prototype. We verified that the system is able to give a real time response, which is linear versus dose and not affected by the high dose rate. The conclusions confirm the capability of the instrument to overcome problems encountered with classic dosimetry, showing that the obtained results strongly encourage the continuation of this research.

Paper Details

Date Published: 24 September 2007
PDF: 8 pages
Proc. SPIE 6706, Hard X-Ray and Gamma-Ray Detector Physics IX, 67061H (24 September 2007); doi: 10.1117/12.739006
Show Author Affiliations
R. Brancaccio, Univ. of Bologna (Italy)
INFN (Italy)
M. Bettuzzi, Univ. of Bologna (Italy)
INFN (Italy)
F. Casali, Univ. of Bologna (Italy)
INFN (Italy)
M. P. Morigi, Univ. of Bologna (Italy)
INFN (Italy)
A. Berdondini, Univ. of Bologna (Italy)
INFN (Italy)
C. Bruno, Univ. of Cosenza (Italy)
INFN (Italy)
Y. F. Tchuente Siaka, Univ. of Cosenza (Italy)
INFN (Italy)
A. Santaniello, Univ. of Cosenza (Italy)
INFN (Italy)
E. Lamanna, Univ. of Cosenza (Italy)
INFN (Italy)
Magna Graecia Univ. (Italy)
A. S. Fiorillo, Magna Graecia Univ. (Italy)
G. Barca, Mariano Santo Hospital (Italy)
F. Castrovillari, Mariano Santo Hospital (Italy)

Published in SPIE Proceedings Vol. 6706:
Hard X-Ray and Gamma-Ray Detector Physics IX
Ralph B. James; Arnold Burger; Larry A. Franks, Editor(s)

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