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Proceedings Paper

Automated slide-screening platform for histo/pathology
Author(s): Rainer Daum; Andreas Achtermann; Rainer Uhl
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Paper Abstract

We have developed a novel platform-concept, which allows the construction of an automated upright light-microscope-based slide-scanning device. In order to achieve maximal speed at maximal image quality we have paid special attention to a highly rigid, highly stiff construction. By using novel materials we have been able to achieve vibration-damping characteristics many times better than conventional approaches. We have combined these new concepts with a voice-coil based digitally controlled focus drive, which achieves the speed and stability of a piezo-element, yet allows travels of up to 10 mm. Using scan-modes which avoid stop & go but instead keep the slide moving at a constant speed we have been able to cut scan-times to levels approaching that of multi-objective approaches, yet with much higher flexibility and better image quality.

Paper Details

Date Published: 18 July 2007
PDF: 10 pages
Proc. SPIE 6631, Novel Optical Instrumentation for Biomedical Applications III, 66311D (18 July 2007); doi: 10.1117/12.729554
Show Author Affiliations
Rainer Daum, TILL Photonics GmbH (Germany)
Andreas Achtermann, TILL Photonics GmbH (Germany)
Rainer Uhl, TILL Photonics GmbH (Germany)
Ludwig-Maximilians-Univ. Munich (Germany)

Published in SPIE Proceedings Vol. 6631:
Novel Optical Instrumentation for Biomedical Applications III
Christian D. Depeursinge, Editor(s)

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