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Proceedings Paper

Optimization of an advanced non-invasive light activated disinfection strategy
Author(s): S. George; A. Kishen
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Paper Abstract

A photosensitizer formulation and strategy was developed based on the photophysical, photochemical and photobiological characteristics of methylene blue (MB) for the disinfection of root canal using light activated therapy. Disinfection of matured E. faecalis biofilms on root canal dentine was tried with the newly developed 'Advanced Non- Invasive Light Activated Disinfection' (ANILAD), conventional photodynamic therapy, and conventional root canal therapy alone or in combination with ANILAD. The results showed that, although complete disinfection of nonmatured biofilm is possible by ANILAD alone, a combination of conventional root canal treatment (RCT) with ANILAD could achieve significantly higher bacterial killing (6log10-7log10 bacterial reduction) compared to any other tested treatment in matured biofilm (p<0.001).

Paper Details

Date Published: 13 July 2007
PDF: 10 pages
Proc. SPIE 6633, Biophotonics 2007: Optics in Life Science, 663318 (13 July 2007); doi: 10.1117/12.729439
Show Author Affiliations
S. George, National Univ. of Singapore (Singapore)
A. Kishen, National Univ. of Singapore (Singapore)

Published in SPIE Proceedings Vol. 6633:
Biophotonics 2007: Optics in Life Science
Jürgen Popp; Gert von Bally, Editor(s)

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