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Proceedings Paper

Time-resolved measurement of the scattered light with an interferometric method based on the use of a camera
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Paper Abstract

We have already demonstrated the potentiality of interferometry to perform timeresolved measurements of the light scattered by a tissue: the fluctuations of the speckle pattern, linked to a wavelength-modulation of the source, are registered, and the time-resolved average intensity can be numerically obtained from these data[1]. The competitive results were obtained with a simple photodiode as detector[2]. Such a method can be cheaper and more accessible for biomedical applications than direct time-resolved methods, but it is not its unique advantage: this method allows to perform Diffusing Wave Spectroscopy (DWS) with selected photon pathlengths[3,4]; for instance, we have shown that we can improve the spatial resolution in transillumination imaging of a dynamic heterogeneity through the selection of short photon transit times[4]. Therefore such a method can offer interesting applications, for example in mammography. A way to improve the signal to noise ratio of this method can consist in multiplying the number of detectors. That's the reason why we decide to consider the use of a high speed camera, that can reach a rate of 1000 frames per second. We will present the first results obtained with this new system. The performance will be discussed, and compared to our previous setup.

Paper Details

Date Published: 12 July 2007
PDF: 10 pages
Proc. SPIE 6629, Diffuse Optical Imaging of Tissue, 66290L (12 July 2007); doi: 10.1117/12.728381
Show Author Affiliations
D. Ettori, Lab. de Physique des Lasers, CNRS, Univ. Paris 13 (France)
K. Zarychta, Lab. de Physique des Lasers, CNRS, Univ. Paris 13 (France)
E. Tinet, Lab. de Physique des Lasers, CNRS, Univ. Paris 13 (France)
S. Avrillier, Lab. de Physique des Lasers, CNRS, Univ. Paris 13 (France)
J.-M. Tualle, Lab. de Physique des Lasers, CNRS, Univ. Paris 13 (France)

Published in SPIE Proceedings Vol. 6629:
Diffuse Optical Imaging of Tissue
Brian W. Pogue; Rinaldo Cubeddu, Editor(s)

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