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Proceedings Paper

Microfluidic chamber with acoustic actuation by LiNbO3 interdigital transducers for tumor cell investigations
Author(s): Matthias Gruber; Richard Heming; Eva-Maria Schnaeker; Thomas Seiler
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Paper Abstract

A microfluidic system is presented that enables in-vitro investigations on tumor cells under conditions similar to those in a blood vessel. Microscopic test objects are immersed in a liquid that circulates in a closed-loop PDMS microchannel and that is sandwiched between a glass and a LiNbO3 wafer which are both transparent to enable visual access. The actuation is achieved electroacoustically by interdigital transducers on the LiNbO3 wafer generating a Rayleigh-type surface acoustic wave that transfers momentum to the liquid. The envisaged medical application for this chamber is briefly sketched, its design and fabrication are discussed, and the operability is demonstrated.

Paper Details

Date Published: 15 May 2007
PDF: 4 pages
Proc. SPIE 6589, Smart Sensors, Actuators, and MEMS III, 65890E (15 May 2007); doi: 10.1117/12.726338
Show Author Affiliations
Matthias Gruber, Univ. of Hagen (Germany)
Richard Heming, Univ. of Hagen (Germany)
Eva-Maria Schnaeker, Univ. of Muenster (Germany)
Thomas Seiler, Univ. of Hagen (Germany)

Published in SPIE Proceedings Vol. 6589:
Smart Sensors, Actuators, and MEMS III
Thomas Becker; Carles Cané; N. Scott Barker, Editor(s)

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