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Proceedings Paper

Quantum dot systems for specific biosensing applications
Author(s): Jay L. Nadeau; Samuel J. Clarke; C. Annette Hollmann; Daniel M. Bahcheli; Rafael A. Khatchadourian; Alexia Bachir; Paul Wiseman
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Paper Abstract

Energy transfer between semiconductor nanoparticles (quantum dots) and energy donors or acceptors modulates fluorescence, thus serving as a visual indicator of the interaction. Careful choice of conjugate or capping groups can thus make these particles serve as sensors for specific biological processes and as tools for targeted cell killing. Challenges include creation of stable conjugates, delivery to specific cell populations and intracellular regions, and characterization of fluorescence modulation by energy transfer.

Paper Details

Date Published: 5 February 2007
PDF: 12 pages
Proc. SPIE 6448, Colloidal Quantum Dots for Biomedical Applications II, 64480M (5 February 2007); doi: 10.1117/12.724218
Show Author Affiliations
Jay L. Nadeau, McGill Univ. (Canada)
Samuel J. Clarke, McGill Univ. (Canada)
C. Annette Hollmann, McGill Univ. (Canada)
Daniel M. Bahcheli, McGill Univ. (Canada)
Rafael A. Khatchadourian, McGill Univ. (Canada)
Alexia Bachir, McGill Univ. (Canada)
Paul Wiseman, McGill Univ. (Canada)

Published in SPIE Proceedings Vol. 6448:
Colloidal Quantum Dots for Biomedical Applications II
Marek Osinski; Thomas M. Jovin; Kenji Yamamoto, Editor(s)

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