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Proceedings Paper

Regularized reconstruction of dynamic gated cardiac SPECT images
Author(s): Mingwu Jin; Yongyi Yang
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Paper Abstract

In this work we propose a spatio-temporal approach for reconstruction of dynamic gated cardiac SPECT images. As in traditional gated cardiac SPECT, the cardiac cycle is divided into a number of gate intervals, but the tracer distribution is treated as a time-varying signal for each gate. Our goal is to produce a dynamic image sequence that shows both cardiac motion and time-varying tracer distribution. To combat the ill-conditioned nature of the problem, we use B-spline basis functions to regulate the time activities curves, and apply a joint MAP estimation approach based on motion compensation for reconstruction of all the different gates. We also explore the benefit of using a time-varying regularization prior for the gated dynamic images. The proposed approach is evaluated using a dynamic version of the 4D gated mathematical cardiac torso phantom (gMCAT) simulating a gated SPECT perfusion acquisition with Technitium-99m labeled Teboroxime.

Paper Details

Date Published: 28 February 2007
PDF: 12 pages
Proc. SPIE 6498, Computational Imaging V, 649805 (28 February 2007); doi: 10.1117/12.714703
Show Author Affiliations
Mingwu Jin, Illinois Institute of Technology (United States)
Yongyi Yang, Illinois Institute of Technology (United States)

Published in SPIE Proceedings Vol. 6498:
Computational Imaging V
Charles A. Bouman; Eric L. Miller; Ilya Pollak, Editor(s)

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