
Proceedings Paper
A computer simulation for evaluating dual-energy contrast-enhanced breast tomosynthesisFormat | Member Price | Non-Member Price |
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Paper Abstract
Previous studies have suggested that iodine contrast-enhanced breast tomosynthesis can be helpful in the
characterization of suspicious abnormalities. Dual-energy, contrast-enhanced breast tomosynthesis involves acquiring
low- and high-energy acquisitions after the administration of the contrast agent, and therefore can simplify the
procedure and reduce the effect of patient motion. In this study, a computer simulation is developed for use in
investigating optimal parameters for dual-energy, contrast-enhanced breast tomosynthesis. The simulation allows for the
selection of various polyenergetic x-ray spectra and x-ray filters, and models x-ray transport through a voxelized breast
phantom, as well as signal and noise propagation through an indirect CsI based imager. A compressed breast phantom
that models the non-uniform parenchymal structure of the breast is used. Irregular lesions were simulated by using a
stochastic growth algorithm. Simulations of dual-energy subtraction, contrast-enhanced breast tomosynthesis show that
using x-ray filters to form quasi-monochromatic high- and low-energy spectra above and below the iodine K-edge can
substantially reduce background structure, and increase lesion conspicuity as compared to single shot contrast-enhanced
BT.
Paper Details
Date Published: 19 March 2007
PDF: 7 pages
Proc. SPIE 6510, Medical Imaging 2007: Physics of Medical Imaging, 65102V (19 March 2007); doi: 10.1117/12.713817
Published in SPIE Proceedings Vol. 6510:
Medical Imaging 2007: Physics of Medical Imaging
Jiang Hsieh; Michael J. Flynn, Editor(s)
PDF: 7 pages
Proc. SPIE 6510, Medical Imaging 2007: Physics of Medical Imaging, 65102V (19 March 2007); doi: 10.1117/12.713817
Show Author Affiliations
Stephen J. Glick, Univ. of Massachusetts Medical School (United States)
Clay Didier, Univ. of Massachusetts at Lowell (United States)
Published in SPIE Proceedings Vol. 6510:
Medical Imaging 2007: Physics of Medical Imaging
Jiang Hsieh; Michael J. Flynn, Editor(s)
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