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Proceedings Paper

Automatic selection of region of interest for radiographic texture analysis
Author(s): Li Lan; Maryellen L. Giger; Joel R. Wilkie; Tamara J. Vokes; Weijie Chen; Hui Li; Tracy Lyons; Michael R. Chinander; Ann Pham
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Paper Abstract

We have been developing radiographic texture analysis (RTA) for assessing osteoporosis and the related risk of fracture. Currently, analyses are performed on heel images obtained from a digital imaging device, the GE/Lunar PIXI, that yields both the bone mineral density (BMD) and digital images (0.2-mm pixels; 12-bit quantization). RTA is performed on the image data in a region-of-interest (ROI) placed just below the talus in order to include the trabecular structure in the analysis. We have found that variations occur from manually selecting this ROI for RTA. To reduce the variations, we present an automatic method involving an optimized Canny edge detection technique and parameterized bone segmentation, to define bone edges for the placement of an ROI within the predominantly calcaneus portion of the radiographic heel image. The technique was developed using 1158 heel images and then tested on an independent set of 176 heel images. Results from a subjective analysis noted that 87.5% of ROI placements were rated as "good". In addition, an objective overlap measure showed that 98.3% of images had successful ROI placements as compared to placement by an experienced observer at an overlap threshold of 0.4. In conclusion, our proposed method for automatic ROI selection on radiographic heel images yields promising results and the method has the potential to reduce intra- and inter-observer variations in selecting ROIs for radiographic texture analysis.

Paper Details

Date Published: 30 March 2007
PDF: 7 pages
Proc. SPIE 6514, Medical Imaging 2007: Computer-Aided Diagnosis, 651436 (30 March 2007); doi: 10.1117/12.711531
Show Author Affiliations
Li Lan, The Univ. of Chicago (United States)
Maryellen L. Giger, The Univ. of Chicago (United States)
Joel R. Wilkie, The Univ. of Chicago (United States)
Tamara J. Vokes, The Univ. of Chicago (United States)
Weijie Chen, The Univ. of Chicago (United States)
Hui Li, The Univ. of Chicago (United States)
Tracy Lyons, The Univ. of Chicago (United States)
Michael R. Chinander, The Univ. of Chicago (United States)
Ann Pham, The Univ. of Chicago (United States)

Published in SPIE Proceedings Vol. 6514:
Medical Imaging 2007: Computer-Aided Diagnosis
Maryellen L. Giger; Nico Karssemeijer, Editor(s)

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