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Proceedings Paper

A 3D visualization and guidance system for handheld optical imaging devices
Author(s): Fred S. Azar; Benoit de Roquemaurel; Albert Cerussi; Nassim Hajjioui; Ang Li; Bruce J. Tromberg; Frank Sauer
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Paper Abstract

We have developed a novel 3D visualization and guidance system for handheld optical imaging devices. In this paper, the system is applied to measurements of breast/cancerous tissue optical properties using a handheld diffuse optical spectroscopy (DOS) instrument. The combined guidance system/DOS instrument becomes particularly useful for monitoring neoadjuvant chemotherapy in breast cancer patients and for longitudinal studies where measurement reproducibility is critical. The system uses relatively inexpensive hardware components and comprises a 6 degrees-of-freedom (DOF) magnetic tracking device including a DC field generator, three sensors, and a PCI card running on a PC workstation. A custom-built virtual environment combined with a well-defined workflow provide the means for image-guided measurements, improved longitudinal studies of breast optical properties, 3D reconstruction of optical properties within the anatomical map, and serial data registration. The DOS instrument characterizes tissue function such as water, lipid and total hemoglobin concentration. The patient lies on her back at a 45-degrees angle. Each spectral measurement requires consistent contact with the skin, and lasts about 5-10 seconds. Therefore a limited number of positions may be studied. In a reference measurement session, the physician acquires surface points on the breast. A Delaunay-based triangulation algorithm is used to build the virtual breast surface from the acquired points. 3D locations of all DOS measurements are recorded. All subsequently acquired surfaces are automatically registered to the reference surface, thus allowing measurement reproducibility through image guidance using the reference measurements.

Paper Details

Date Published: 21 March 2007
PDF: 12 pages
Proc. SPIE 6509, Medical Imaging 2007: Visualization and Image-Guided Procedures, 650909 (21 March 2007); doi: 10.1117/12.710506
Show Author Affiliations
Fred S. Azar, Siemens Corporate Research (United States)
Benoit de Roquemaurel, Siemens Corporate Research (United States)
Albert Cerussi, Univ. of California, Irvine (United States)
Nassim Hajjioui, Siemens Corporate Research (United States)
Ang Li, Univ. of California, Irvine (United States)
Bruce J. Tromberg, Univ. of California, Irvine (United States)
Frank Sauer, Siemens Corporate Research (United States)

Published in SPIE Proceedings Vol. 6509:
Medical Imaging 2007: Visualization and Image-Guided Procedures
Kevin R. Cleary; Michael I. Miga, Editor(s)

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