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Proceedings Paper

Dual-energy contrast enhanced digital breast tomosynthesis: concept, method, and evaluation on phantoms
Author(s): Sylvie Puong; Fanny Patoureaux; Razvan Iordache; Xavier Bouchevreau; Serge Muller
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Paper Abstract

In this paper, we present the development of dual-energy Contrast-Enhanced Digital Breast Tomosynthesis (CEDBT). A method to produce background clutter-free slices from a set of low and high-energy projections is introduced, along with a scheme for the determination of the optimal low and high-energy techniques. Our approach consists of a dual-energy recombination of the projections, with an algorithm that has proven its performance in Contrast-Enhanced Digital Mammography1 (CEDM), followed by an iterative volume reconstruction. The aim is to eliminate the anatomical background clutter and to reconstruct slices where the gray level is proportional to the local iodine volumetric concentration. Optimization of the low and high-energy techniques is performed by minimizing the total glandular dose to reach a target iodine Signal Difference to Noise Ratio (SDNR) in the slices. In this study, we proved that this optimization could be done on the projections, by consideration of the SDNR in the projections instead of the SDNR in the slices, and verified this with phantom measurements. We also discuss some limitations of dual-energy CEDBT, due to the restricted angular range for the projection views, and to the presence of scattered radiation. Experiments on textured phantoms with iodine inserts were conducted to assess the performance of dual-energy CEDBT. Texture contrast was nearly completely removed and the iodine signal was enhanced in the slices.

Paper Details

Date Published: 21 March 2007
PDF: 12 pages
Proc. SPIE 6510, Medical Imaging 2007: Physics of Medical Imaging, 65100U (21 March 2007); doi: 10.1117/12.710106
Show Author Affiliations
Sylvie Puong, Univ. Paris XI (France)
GE Healthcare (France)
Fanny Patoureaux, GE Healthcare (France)
Razvan Iordache, GE Healthcare (France)
Xavier Bouchevreau, Altran (France)
Serge Muller, GE Healthcare (France)

Published in SPIE Proceedings Vol. 6510:
Medical Imaging 2007: Physics of Medical Imaging
Jiang Hsieh; Michael J. Flynn, Editor(s)

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