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Proceedings Paper

An evaluation of 3D modality independent elastography robustness to boundary condition noise
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Paper Abstract

This work explores an inverse problem technique of extracting soft tissue elasticity information via nonrigid model-based image registration. The algorithm uses the elastic properties of the tissue in a biomechanical model to achieve maximal similarity between image data acquired under different states of loading. A framework capable of handling fully three-dimensional models and image data has been recently developed utilizing parallel computing and iterative sparse matrix solvers. For this preliminary investigation, a series of simulation experiments with clinical image data of human breast are used to test the robustness of the algorithm to expected mis-estimation of displacement boundary conditions encountered in real-world situations. Three methods of automated point correspondence are also examined as means of generating boundary conditions for the algorithm.

Paper Details

Date Published: 29 March 2007
PDF: 9 pages
Proc. SPIE 6511, Medical Imaging 2007: Physiology, Function, and Structure from Medical Images, 65111X (29 March 2007); doi: 10.1117/12.709944
Show Author Affiliations
Jao J. Ou, Vanderbilt Univ. (United States)
Rowena E. Ong, Vanderbilt Univ. (United States)
Michael I. Miga, Vanderbilt Univ. (United States)

Published in SPIE Proceedings Vol. 6511:
Medical Imaging 2007: Physiology, Function, and Structure from Medical Images
Armando Manduca; Xiaoping P. Hu, Editor(s)

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