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Proceedings Paper

Propagation of diffused light modulated by a focused ultrasound in scattering media
Author(s): Lili Zhu; Hui Li; Jiali Cai; Cuncheng Weng; Shusen Xie
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Paper Abstract

Ultrasound-modulated optical tomography is a promising and noninvasive method for biomedical imaging. The advantage of this technology is its combination of optical contrast and ultrasonic resolution. In order to reconstruct the tissue imaging effectively and reliably, the propagation of the light modulated by ultrasound in the tissue should be understood extensively. In our opinion, there are three light transport processes in tissue as follows: Firstly, the incident light goes from the surface to the focused region. If the distance, tagged as Iis long enough (Z>>mfp, mean free path). the light transport obeys diffuse theory. Secondly, the diffuse light can be modulated in the focused region at Z due to the light-sound interaction. Finally, the modulation light from the Z can be regarded as a spot light source which emits the ballistic or snake photons to reach the surface and so as to be collected by a detector outside of tissue in the third process. the propagation of the diffused light modulated by ultrasound play an important role in particularly because it reflects some information about the optical and ultrasonic properties of tissue. Based on the Monte Carlo simulation, the relations to the modulation light intensity and its modulation depth contributed by the tissue thickness, optical properties, etc. are figured out and supported by an equivalent experiment and at an extended condition also agree with the diffuse theory.

Paper Details

Date Published: 27 October 2006
PDF: 7 pages
Proc. SPIE 6047, Fourth International Conference on Photonics and Imaging in Biology and Medicine, 60470B (27 October 2006); doi: 10.1117/12.709838
Show Author Affiliations
Lili Zhu, Fujian Normal Univ. (China)
Hui Li, Fujian Normal Univ. (China)
Jiali Cai, Fujian Normal Univ. (China)
Cuncheng Weng, Fujian Normal Univ. (China)
Shusen Xie, Fujian Normal Univ. (China)

Published in SPIE Proceedings Vol. 6047:
Fourth International Conference on Photonics and Imaging in Biology and Medicine
Kexin Xu; Qingming Luo; Da Xing; Alexander V. Priezzhev; Valery V. Tuchin, Editor(s)

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