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Proceedings Paper

Multi-center MRI volume and linearity behavior
Author(s): M. Barbu-McInnis; L. Molinelli; E. Durkin; J. Tamez-Peña; S. Totterman
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Paper Abstract

Accurate longitudinal measurements are essential in understanding treatment effectiveness. Miss-calibrated gradients, low acquisition bandwidth, or abnormally high B0 inhomogeneities may cause geometric distortions in the MRI, which in turn may affect the imaging based biomarkers used to understand disease progression. This work presents the behavior of several MRI sites over an average period of 12 months using the analysis of a volume and linearity phantom with known geometry. The phantom was scanned in the axial, coronal, and sagittal planes using a T2 FSE sequence. For each month's scan, the average phantom length was measured in the right/left, anterior/posterior, and superior/inferior directions. The distortion variation was measured in each gradient axis and orientation over time. Results show that some magnets exhibit a significant drift within the scanning period. Unless this type of distortion is considered, the treatment efficacy outcome may be annulled due to misleading and erroneous conclusions.

Paper Details

Date Published: 8 March 2007
PDF: 8 pages
Proc. SPIE 6515, Medical Imaging 2007: Image Perception, Observer Performance, and Technology Assessment, 65151Q (8 March 2007); doi: 10.1117/12.709512
Show Author Affiliations
M. Barbu-McInnis, VirtualScopics, Inc. (United States)
L. Molinelli, VirtualScopics, Inc. (United States)
E. Durkin, VirtualScopics, Inc. (United States)
J. Tamez-Peña, VirtualScopics, Inc. (United States)
S. Totterman, VirtualScopics, Inc. (United States)

Published in SPIE Proceedings Vol. 6515:
Medical Imaging 2007: Image Perception, Observer Performance, and Technology Assessment
Yulei Jiang; Berkman Sahiner, Editor(s)

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