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Proceedings Paper

Utilization of a global data grid repository in CAD assessment of carotid wall thickness
Author(s): Marco A. Gutierrez; Jasper Lee; Zheng Zhou; Paulo E. Pilon; Silvia G. Lage
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Paper Abstract

A CAD method of calculating wall thickness of carotid vessels addresses the time-consuming issue of using B-mode ultrasound as well as inter- and intra-observer variability in results. Upon selection of a region-of-interest and filtering of a series of ultrasound carotid images, the CAD is able to measure the geometry of the lumen and plaque surfaces using a least-square fitting of the active contours during systole and diastole. To evaluate the approach, ultrasound image sequences from 30 patients were submitted to the procedure. The images were stored on an international data grid repository that consists of three international sites: Image Processing and Informatics (IPI) Laboratory at University of Southern California, USA; InCor (Heart Institute) at Sao Paulo, Brazil, and Hong Kong Polytechnic University, Hong Kong. The three chosen sites are connected with high speed international networks including the Internet2, and the Brazilian National Research and Education Network (RNP2). The Data Grid was used to store, backup, and share the ultrasound images and analysis results, which provided a large-scale and a virtual data system. In order to study the variability between the automatic and manual definition of artery boundaries, the pooled mean and the standard deviation for the difference between measurements of lumen diameter were computed. The coefficient of variation and correlation were also calculated. For the studied population the difference between manual and automatic measurement of the lumen diameter (LD) and intima-media-thickness (IMT) were 0.12 +/-0.10 and 0.09+/- 0.06, respectively.

Paper Details

Date Published: 21 March 2007
PDF: 10 pages
Proc. SPIE 6516, Medical Imaging 2007: PACS and Imaging Informatics, 651614 (21 March 2007); doi: 10.1117/12.709311
Show Author Affiliations
Marco A. Gutierrez, Heart Institute, Univ. of Sao Paulo Medical School (Brazil)
Jasper Lee, Univ. of Southern California (United States)
Zheng Zhou, Univ. of Southern California (United States)
Paulo E. Pilon, Heart Institute, Univ. of Sao Paulo Medical School (Brazil)
Silvia G. Lage, Heart Institute, Univ. of Sao Paulo Medical School (Brazil)

Published in SPIE Proceedings Vol. 6516:
Medical Imaging 2007: PACS and Imaging Informatics
Steven C. Horii; Katherine P. Andriole, Editor(s)

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