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Proceedings Paper

Molecular and structural analysis of viscoelastic properties
Author(s): Rebecca D. Yapp; Sureshkumar Kalyanam; Michael F. Insana
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Paper Abstract

Elasticity imaging is emerging as an important tool for breast cancer detection and monitoring of treatment. Viscoelastic image contrast in breast lesions is generated by disease specific processes that modify the molecular structure of connective tissues. We showed previously that gelatin hydrogels exhibit mechanical behavior similar to native collagen found in breast tissue and therefore are suitable as phantoms for elasticity imaging. This paper summarizes our study of the viscoelastic properties of hydrogels designed to discover molecular-scale sources of elasticity image contrast.

Paper Details

Date Published: 10 May 2007
PDF: 11 pages
Proc. SPIE 6511, Medical Imaging 2007: Physiology, Function, and Structure from Medical Images, 65111Y (10 May 2007); doi: 10.1117/12.708723
Show Author Affiliations
Rebecca D. Yapp, Univ. of Illinois at Urbana-Champaign/Beckman Institute for Advanced Science and Technology (United States)
Sureshkumar Kalyanam, Univ. of Illinois at Urbana-Champaign/Beckman Institute for Advanced Science and Technology (United States)
Michael F. Insana, Univ. of Illinois at Urbana-Champaign/Beckman Institute for Advanced Science and Technology (United States)


Published in SPIE Proceedings Vol. 6511:
Medical Imaging 2007: Physiology, Function, and Structure from Medical Images
Armando Manduca; Xiaoping P. Hu, Editor(s)

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