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Proceedings Paper

High isotropic resolution PS-OCT for imaging the human retina and cone mosaic in vivo
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Paper Abstract

We present a system for high and isotropic resolution imaging of the retina. A polarization sensitive optical coherence tomography (PS-OCT) instrument with a depth resolution of ~4.5&mgr;m within the retina was used and adapted to achieve a high transverse resolution. The realized transverse resolution was sufficient to resolve the human cone mosaic in vivo without the use of adaptive optics. Since the technique is based on a fast transversal scanning of the retina, scanning laser ophthalmoscope (SLO) images can be acquired simultaneously to OCT images which allows a direct comparison of the two techniques. Furthermore, the system incorporates the possibility of a dynamic shift of focus within the retina which is essential to maintain the high transverse resolution over the whole imaging depth. Using a resonant scanner operated at 4kHz the system is capable to record 8000 transversal lines per second. Backscattered intensity, retardation and fast axis orientation of the human retina are presented with this high isotropic resolution.

Paper Details

Date Published: 5 March 2007
PDF: 5 pages
Proc. SPIE 6426, Ophthalmic Technologies XVII, 64260J (5 March 2007);
Show Author Affiliations
M. Pircher, Medical Univ. of Vienna (Austria)
B. Baumann, Medical Univ. of Vienna (Austria)
E. Götzinger, Medical Univ. of Vienna (Austria)
C. K. Hitzenberger, Medical Univ. of Vienna (Austria)

Published in SPIE Proceedings Vol. 6426:
Ophthalmic Technologies XVII
Bruce E. Stuck; Fabrice Manns; Per G. Söderberg; Michael Belkin M.D.; Arthur Ho, Editor(s)

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