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Proceedings Paper

Doppler spectroscopy of blood in capillary plexus under the action of 40% glucose solution
Author(s): A. N. Korolevich; A. Yelshin; M. Belsley; M. Mota
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Paper Abstract

The investigation of blood dynamical characteristics in the skin under the action of 40% glucose solution was performed in vivo by the laser Doppler technique. Experiments demonstrate that glucose solution affects significantly the blood perfusion and concentration. Qualitative explanation was made for observed perfusion dynamic effect in the skin dermis based on the following factors: tissue cells shrinkage and additional capillaries opening under osmotic stress. The size of glucose vesicle lens was measured under the skin by ultrasonography. The analysis of vesicle sizes monitoring leads to the conclusion that glucose lens spread, basically, along the skin than in the perpendicular to the skin surface direction. Obtained results show the significant anisotropic perturbation of the dynamic characteristics of blood in vascular plexus under the optical active solution influence that must be taken into consideration during optical clarification of biological tissues.

Paper Details

Date Published: 21 July 2006
PDF: 6 pages
Proc. SPIE 6163, Saratov Fall Meeting 2005: Optical Technologies in Biophysics and Medicine VII, 61630I (21 July 2006); doi: 10.1117/12.696961
Show Author Affiliations
A. N. Korolevich, Institute of Physics, National Academy of Sciences of Belarus (Belarus)
Minho Univ. (Portugal)
A. Yelshin, Minho Univ. (Portugal)
M. Belsley, Minho Univ. (Portugal)
M. Mota, Minho Univ. (Portugal)

Published in SPIE Proceedings Vol. 6163:
Saratov Fall Meeting 2005: Optical Technologies in Biophysics and Medicine VII
Valery V. Tuchin, Editor(s)

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