Share Email Print

Proceedings Paper

Multi-modality molecular imaging: pre-clinical laboratory configuration
Author(s): Yanjun Wu; Jeremy W. Wellen; Susanta K. Sarkar
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

In recent years, the prevalence of in vivo molecular imaging applications has rapidly increased. Here we report on the construction of a multi-modality imaging facility in a pharmaceutical setting that is expected to further advance existing capabilities for in vivo imaging of drug distribution and the interaction with their target. The imaging instrumentation in our facility includes a microPET scanner, a four wavelength time-domain optical imaging scanner, a 9.4T/30cm MRI scanner and a SPECT/X-ray CT scanner. An electronics shop and a computer room dedicated to image analysis are additional features of the facility. The layout of the facility was designed with a central animal preparation room surrounded by separate laboratory rooms for each of the major imaging modalities to accommodate the work-flow of simultaneous in vivo imaging experiments. This report will focus on the design of and anticipated applications for our microPET and optical imaging laboratory spaces. Additionally, we will discuss efforts to maximize the daily throughput of animal scans through development of efficient experimental work-flows and the use of multiple animals in a single scanning session.

Paper Details

Date Published: 13 February 2006
PDF: 12 pages
Proc. SPIE 6081, Multimodal Biomedical Imaging, 60810H (13 February 2006); doi: 10.1117/12.660244
Show Author Affiliations
Yanjun Wu, GlaxoSmithKline (United States)
Jeremy W. Wellen, GlaxoSmithKline (United States)
Susanta K. Sarkar, GlaxoSmithKline (United States)

Published in SPIE Proceedings Vol. 6081:
Multimodal Biomedical Imaging
Fred S. Azar; Dimitris N. Metaxas, Editor(s)

© SPIE. Terms of Use
Back to Top
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?