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Proceedings Paper

Absolute flow velocity components in laser Doppler flowmetry
Author(s): Ingemar Fredriksson; Marcus Larsson; Tomas Strömberg
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Paper Abstract

A method to separate a Doppler power spectrum into a number of flow velocity components, measured in absolute units (mm/s), is presented. A Monte Carlo software was developed to track each individual Doppler shift, to determine the probability, p(n), for a photon to undergo n Doppler shifts. Given this shift distribution, a mathematical relationship was developed and used to calculate a Doppler power spectrum originating from a certain combination of velocity components. The non linear Levenberg-Marquardt optimization method could thus be used to fit the calculated and measured Doppler power spectra, giving the true set of velocity components in the measured sample. The method was evaluated using a multi tube flow phantom perfused with either polystyrene microspheres or undiluted/diluted human blood (hct = 0.45). It estimated the velocity components in the flow phantom well, during both low and high concentrations of moving scatterers (microspheres or blood). Thus, further development of the method could prove to be a valuable clinical tool to differentiate capillary blood flow.

Paper Details

Date Published: 27 February 2006
PDF: 12 pages
Proc. SPIE 6094, Optical Diagnostics and Sensing VI, 60940A (27 February 2006); doi: 10.1117/12.659206
Show Author Affiliations
Ingemar Fredriksson, Linköping Univ. (Sweden)
Marcus Larsson, Linköping Univ. (Sweden)
Tomas Strömberg, Linköping Univ. (Sweden)

Published in SPIE Proceedings Vol. 6094:
Optical Diagnostics and Sensing VI
Gerard L. Coté; Alexander V. Priezzhev, Editor(s)

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