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Proceedings Paper

Sensitivity of different light scattering techniques to variations of optical parameters of a blood layer in vitro studied by Monte Carlo simulations
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Paper Abstract

In various publications, the values of blood optical parameters reported or used by different authors dffer dramatically. The aim of the present work is to estimate by means of Monte Carlo simulation the effect of variations of some of these parameters on the signals measured by different light scattering techniques. The following techniques are considered. optical coherence tomography, time-of-flight measurements, goniophotometry, and spectrophotometry implementing the integrating spheres measurements. The base wavelength of 820 mn within the diagnostic window, which is frequently used when implementing the mentioned techniques was chosen for the simulations. It was shown that both scattering coefficient and anisotropy factor affect the output signals. which vary significantly in the considered ranges of the parameters values. The strongest variations are due to varying the anisotropy factor, while varying the scattering coefficient influences primarily the level of the signal, but preserves its shape.

Paper Details

Date Published: 27 February 2006
PDF: 7 pages
Proc. SPIE 6094, Optical Diagnostics and Sensing VI, 60940O (27 February 2006); doi: 10.1117/12.655001
Show Author Affiliations
Mikhail Yu. Kirillin, M.V. Lomonosov Moscow State Univ. (Russia)
Univ. of Oulu (Finland)
Alexander V. Priezzhev, M.V. Lomonosov Moscow State Univ. (Russia)
Jukka Hast, Univ. of Oulu (Finland)
VTT Technical Research Ctr. of Finland (Finland)
Risto Myllylä, Univ. of Oulu (Finland)

Published in SPIE Proceedings Vol. 6094:
Optical Diagnostics and Sensing VI
Gerard L. Coté; Alexander V. Priezzhev, Editor(s)

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