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Proceedings Paper

Visualization of tumor-influenced 3D lung dynamics
Author(s): Anand P. Santhanam; Cali M. Fidopiastis; Katja Langen; Sanford Meeks; Patrick A. Kupelian M.D.; Larry Davis; Jannick P. Rolland
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Paper Abstract

A framework for real-time visualization of a tumor-influenced lung dynamics is presented in this paper. This framework potentially allows clinical technicians to visualize in 3D the morphological changes of lungs under different breathing conditions. Consequently, this technique may provide a sensitive and accurate assessment tool for pre-operative and intra-operative clinical guidance. The proposed simulation method extends work previously developed for modeling and visualizing normal 3D lung dynamics. The model accounts for the changes in the regional lung functionality and the global motor response due to the presence of a tumor. For real-time deformation purposes, we use a Green's function (GF), a physically based approach that allows real-time multi-resolution modeling of the lung deformations. This function also allows an analytical estimation of the GF's deformation parameters from the 4D lung datasets at different level-of-details of the lung model. Once estimated, the subject-specific GF facilitates the simulation of tumor-influenced lung deformations subjected to any breathing condition modeled by a parametric Pressure-Volume (PV) relation.

Paper Details

Date Published: 10 March 2006
PDF: 12 pages
Proc. SPIE 6141, Medical Imaging 2006: Visualization, Image-Guided Procedures, and Display, 61410C (10 March 2006); doi: 10.1117/12.654099
Show Author Affiliations
Anand P. Santhanam, Univ. of Central Florida (United States)
Cali M. Fidopiastis, Univ. of Central Florida (United States)
Katja Langen, M.D. Anderson Cancer Ctr. (United States)
Sanford Meeks, M.D. Anderson Cancer Ctr. (United States)
Patrick A. Kupelian M.D., M.D. Anderson Cancer Ctr. (United States)
Larry Davis, Tirrion Technologies (United States)
Jannick P. Rolland, Univ. of Central Florida (United States)
CREOL, College of Optics and Photonics, Univ. of Central Florida (United States)

Published in SPIE Proceedings Vol. 6141:
Medical Imaging 2006: Visualization, Image-Guided Procedures, and Display
Kevin R. Cleary; Robert L. Galloway, Jr., Editor(s)

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