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Proceedings Paper

Discrete tomography from micro-CT data: application to the mouse trabecular bone structure
Author(s): K. J. Batenburg; J. Sijbers
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Paper Abstract

Discrete Tomography (DT) deals with the reconstruction of an image from its projections when this image is known to have only a small number of gray values. The knowledge of the discrete set of gray values can significantly reduce the number of projections required for a high-quality reconstruction. In this paper, a feasibility study is presented of the application of discrete tomography to micro-CT data from a mouse leg as to study the structural properties of the trabecular bone. The set of gray values is restricted to only three values, for the air background, the soft tissue background, and the trabecular bone structure. Reconstructions of the trabecular bone structure are usually obtained by computing a continuous reconstruction. To extract morphometric information from the reconstruction, the image must be segmented into the different tissue types, which is commonly done by thresholding. In the DT approach such a segmentation step is no longer necessary, as the reconstruction already contains a single gray value for each tissue type. Our results show that by using discrete tomography, a much better reconstruction of the trabecular bone structure can be obtained than by thresholding a continuous reconstruction from the same number of projections.

Paper Details

Date Published: 2 March 2006
PDF: 11 pages
Proc. SPIE 6142, Medical Imaging 2006: Physics of Medical Imaging, 614240 (2 March 2006); doi: 10.1117/12.652603
Show Author Affiliations
K. J. Batenburg, Leiden Univ. (Netherlands)
Ctr. voor Wiskunde en Informatica (Netherlands)
J. Sijbers, Univ. of Antwerp (Belgium)

Published in SPIE Proceedings Vol. 6142:
Medical Imaging 2006: Physics of Medical Imaging
Michael J. Flynn; Jiang Hsieh, Editor(s)

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