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Proceedings Paper

Novel sensor for ultrasensitive and single-molecule detection
Author(s): K. Linga; E. Godik; J. Krutov; V. B. Zaitsev; V. E. Shubin; D. A. Shushakov; S. L. Vinogradov
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Paper Abstract

The detection and identification of single molecules represent one of the ultimate goals of analytical chemistry. We have designed, developed and tested a new family of photodetectors with Internal Discrete Amplification (IDA) mechanism. These photodetectors can operate in linear (analog) detection mode with gain-bandwidth product up to 5.1014 and one- or few-photon sensitivity, as well as in the photon counting mode with count rates up to 108 cps. Their key performance characteristics exceed those of photomultiplier tube (PMT) and avalanche photodiode (APD) devices. The measured parameters of the detectors are: gain > 105, excess noise factor as low as 1.02, maximum count rate > 108 counts/s, and rise/fall time < 300 ps. The new family of the photo detectors may become an ideal solution for the problems of ultrasensitive and single-molecule detection by fluorescence spectroscopy and other optical methods.

Paper Details

Date Published: 27 February 2006
PDF: 9 pages
Proc. SPIE 6092, Ultrasensitive and Single-Molecule Detection Technologies, 60920X (27 February 2006); doi: 10.1117/12.647150
Show Author Affiliations
K. Linga, Amplification Technologies, Inc. (United States)
E. Godik, Amplification Technologies, Inc. (United States)
J. Krutov, Amplification Technologies, Inc. (United States)
V. B. Zaitsev, Amplification Technologies, Inc. (United States)
V. E. Shubin, Amplification Technologies, Inc. (United States)
D. A. Shushakov, Amplification Technologies, Inc. (United States)
S. L. Vinogradov, Amplification Technologies, Inc. (United States)

Published in SPIE Proceedings Vol. 6092:
Ultrasensitive and Single-Molecule Detection Technologies
Jörg Enderlein; Zygmunt K. Gryczynski, Editor(s)

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