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Proceedings Paper

Prophylactic use of timolol maleate to prevent intraocular pressure elevation after Nd-YAG laser posterior capsulotomy
Author(s): Jiping Cai; Ruili Wei; Xiaoye Ma; Huang Zhu; You Li; Jinwei Cheng; Feng Jiang
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Paper Abstract

Objective: To evaluate the effective prophylaxis of topical 0.5% timolol maleate for the intraocular pressure rise following Nd-YAG laser posterior capsulotomy. Subjects and Methods: One hundred and ninety eyes of 184 patients undergoing Nd-YAG laser posterior capsulotomy were randomly assigned to pretreatment with either topical 0.5% timolol maleate (therapy group) or nothing (control group). Results: The mean IOP of the therapy group was 14.8±3.0 mmHg before capsulotomy and 15.7±3.4 mmHg after capsulotomy (P>0.05), whereas 15.1±3.3 mmHg and 17.2±4.3 mmHg (P<0.05) of the control group. There was no statistically significant difference between the two groups with regard to mean IOP before capsulotomy (P>0.05), but statistically significant difference between two groups after capsulotomy (P<0.05). Six of 91 eyes (6.6%, 2 aphakias included) of the therapy group had an IOP elevation greater than 6 mmHg compared with 14 of 99 eyes (14.1%, 8 aphakias included) of the control group (P<0.01). Conclusion: The pretreatment with topical 0.5% timolol maleate is effective in preventing IOP elevation after Nd-YAG laser posterior capsulotomy.

Paper Details

Date Published: 11 September 2006
PDF: 4 pages
Proc. SPIE 5967, 2004 Shanghai International Conference on Laser Medicine and Surgery, 59671L (11 September 2006); doi: 10.1117/12.639340
Show Author Affiliations
Jiping Cai, Second Military Medical Univ. (China)
Ruili Wei, Second Military Medical Univ. (China)
Xiaoye Ma, Second Military Medical Univ. (China)
Huang Zhu, Second Military Medical Univ. (China)
You Li, Second Military Medical Univ. (China)
Jinwei Cheng, Second Military Medical Univ. (China)
Feng Jiang, Second Military Medical Univ. (China)

Published in SPIE Proceedings Vol. 5967:
2004 Shanghai International Conference on Laser Medicine and Surgery
Jing Zhu, Editor(s)

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