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Proceedings Paper • Open Access

Interaction and intelligence in living neuronal networks interfaced with moving robot

Paper Abstract

Neurons form complex networks and it seems that the living neuronal network can perform certain type of information processing. We are interested in intelligence autonomously formed in vitro. The most important features of the two-dimensional culture neural network are that it is a system in which the information processing is autonomously carries out. We reported previously that the functional connections were dynamically modified by synaptic potentiation and the process may be required for reorganization of the functional group of neurons. Such neuron assemblies are critical for information processing in brain. Certain types of feedback stimulation caused suppression of spontaneous network electrical activities and drastic re-organization of functional connections between neurons, when these activities are initially almost synchronized. The result suggests that neurons in dissociated culture autonomously re-organized their functional neuronal networks interacted with their environment. The spatio-temporal pattern of activity in the networks may be a reflection of their external environment. We also interfaced the cultured neuronal network with moving robot. The planar microelectrodes can be used for detecting neuronal electrical signals from the living neuronal network cultured on a 2-dimensional electrode array. The speed of actuators of moving robot was determined by these detected signals. Our goal is reconstruction of the neural network, which can process "thinking" in the dissociated culture system.

Paper Details

Date Published: 19 January 2006
PDF: 12 pages
Proc. SPIE 6036, BioMEMS and Nanotechnology II, 60360S (19 January 2006); doi: 10.1117/12.638434
Show Author Affiliations
Suguru N. Kudoh, National Institute of Advanced Industrial Science and Technology (Japan)
PRESTO, Japan Science and Technology Agency (Japan)
Takahisa Taguchi, National Institute of Advanced Industrial Science and Technology (Japan)

Published in SPIE Proceedings Vol. 6036:
BioMEMS and Nanotechnology II
Dan V. Nicolau, Editor(s)

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