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Proceedings Paper

Monte Carlo simulation for the optical transmittance in biological tissues during the action of osmotic agents
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Paper Abstract

Computational methods have been used with great application to biomedical optics. The events created by the interaction of radiation with biological materials can easily be translated to computer languages with the objective of producing simulation techniques to be used prior to physical intervention. The addition of biocompatible and hyper osmotic agents to several types of biological tissues has proven the enhancement of transparency to radiation flux by reduction of material's optical properties. The evolutionary behavior of the agent's action in the tissue samples before saturation has been observed by numerous researchers but has never been described mathematically. In the present work we will describe the application of Monte Carlo simulation to estimate the evolutionary states of optical transparency of biological tissues when immersed in an osmotic solution. We begin our study with typical values for the optical properties of rabbit muscle and proceed by reducing the absorption and scattering coefficients independently and simultaneously. The results show the number of transmitted, absorbed, scattered and reflected photons in different stages of the action of a generic osmotic agent over a small and well defined tissue sample.

Paper Details

Date Published: 22 June 2005
PDF: 12 pages
Proc. SPIE 5771, Saratov Fall Meeting 2004: Optical Technologies in Biophysics and Medicine VI, (22 June 2005); doi: 10.1117/12.634821
Show Author Affiliations
L. Oliveira, CETO--Ctr. de Ciencias e Tecnologias Opticas (Portugal)
Armindo Lage, CETO--Ctr. de Ciencias e Tecnologias Opticas (Portugal)

Published in SPIE Proceedings Vol. 5771:
Saratov Fall Meeting 2004: Optical Technologies in Biophysics and Medicine VI
Valery V. Tuchin, Editor(s)

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