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Proceedings Paper

A transducer-independent optical sensor system for the detection of biochemical binding reactions
Author(s): Rüdiger Frank; Bernd Möhrle; Dieter Fröhlich; Günter Gauglitz
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Paper Abstract

In this article we present a very simple, transducer-independent label-free optical detection method based on reflectometry for bioanalytical applications. A laboratory setup of this 1λ-reflectometry delivers results that are comparable with established detection principles like Surface Plasmon Resonance or Reflectometric Interference Spectroscopy. Additionally we present a first version of a miniaturized setup of this method to show its potential due to its simplicity.

Paper Details

Date Published: 8 November 2005
PDF: 11 pages
Proc. SPIE 5993, Advanced Environmental, Chemical, and Biological Sensing Technologies III, 59930A (8 November 2005); doi: 10.1117/12.633881
Show Author Affiliations
Rüdiger Frank, Eberhard Karls Univ. Tübingen (Germany)
Bernd Möhrle, Eberhard Karls Univ. Tübingen (Germany)
Dieter Fröhlich, Eberhard Karls Univ. Tübingen (Germany)
Günter Gauglitz, Eberhard Karls Univ. Tübingen (Germany)

Published in SPIE Proceedings Vol. 5993:
Advanced Environmental, Chemical, and Biological Sensing Technologies III
Tuan Vo-Dinh; Robert A. Lieberman; Gunter Gauglitz, Editor(s)

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