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Proceedings Paper

Reflectance measurements of skin lesions: noninvasive method for diagnostic evaluation of pigmented neoplasia
Author(s): E. Borisova; P. Trojanova M.D.; L. Avramov
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Paper Abstract

The aims of this work are investigation and differentiation between normal skin and pigmented skin lesions by using optical reflectance spectroscopy. Optical reflectance spectra in the wavelength range 400-900 nm were obtained from malignant and benign skin lesions and characteristic differences between them were studied. The lesions were preliminarily classified dermatoscopically (MoleMax II, DERMA Instruments). All suspicious lesions were excised and the materials were investigated histologically by standard methods. An algorithm was developed for differentiation and valuation of the skin tissue condition using dimensionless ratios of the reflectance signal intensities of normal skin and pigmented lesions, which allowed the use of non-normalized reflectance spectra for lesion assessment. These ratios were found to have a definite diagnostic potential, as significant differences were observed between normal skin, benign and malignant pigmented lesions.

Paper Details

Date Published: 7 October 2005
PDF: 11 pages
Proc. SPIE 5862, Diagnostic Optical Spectroscopy in Biomedicine III, 58620A (7 October 2005); doi: 10.1117/12.633013
Show Author Affiliations
E. Borisova, Institute of Electronics (Bulgaria)
P. Trojanova M.D., National Oncological Ctr. (Bulgaria)
L. Avramov, Institute of Electronics (Bulgaria)

Published in SPIE Proceedings Vol. 5862:
Diagnostic Optical Spectroscopy in Biomedicine III
Mary-Ann Mycek, Editor(s)

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