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Proceedings Paper

Biomolecule-less sensors for biomolecules based on templated xerogel platforms
Author(s): Zunyu Tao; Elizabeth C. Tehan; Rachel M. Bukowski; Ying Tang; Ellen L. Shughart; William G. Holthoff; Alexander N. Cartwright; Albert H. Titus; Frank V. Bright
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Paper Abstract

We report on a new strategy for producing self-contained sensor elements for protein detection. The method exploits molecular imprinting, sol-gel-derived xerogels, and selective installation of the fluorescent reporter molecule within the template site. There are no biological reagents used. We term these new xerogel-based sensor elements as Protein Imprinted Xerogels with Integrated Emission Sites (PIXIES). The analytical figures of merit are described.

Paper Details

Date Published: 12 October 2005
PDF: 9 pages
Proc. SPIE 5969, Photonic Applications in Biosensing and Imaging, 59690F (12 October 2005); doi: 10.1117/12.629169
Show Author Affiliations
Zunyu Tao, State Univ. of New York/Buffalo (United States)
Elizabeth C. Tehan, State Univ. of New York/Buffalo (United States)
Rachel M. Bukowski, State Univ. of New York/Buffalo (United States)
Ying Tang, State Univ. of New York/Buffalo (United States)
Ellen L. Shughart, State Univ. of New York/Buffalo (United States)
William G. Holthoff, State Univ. of New York/Buffalo (United States)
Alexander N. Cartwright, State Univ. of New York/Buffalo (United States)
Albert H. Titus, State Univ. of New York/Buffalo (United States)
Frank V. Bright, State Univ. of New York/Buffalo (United States)


Published in SPIE Proceedings Vol. 5969:
Photonic Applications in Biosensing and Imaging
Brian C. Wilson; Richard I. Hornsey; Warren C. W. Chan; Ulrich J. Krull; Robert A. Weersink; Kui Yu, Editor(s)

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