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Proceedings Paper

Optical spectroscopy for quantification of bulk breast tissue properties in adolescent girls: preliminary observations
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Paper Abstract

Optical technology holds considerable promise to improve early detection, diagnosis and risk assessment of breast cancer. Unlike current clinical risk assessment tools such as the Gail model, the most widely accepted risk assessment tool, optical risk assessment technology can be applied to the entire female population of all ages. This study is investigating the use of optical reflectance spectroscopy (ORS) as a possible breast tissue development monitoring tool for adolescent girls. Changes in breast development due to proliferation of mammary gland and the surrounding stroma are reflected in changes in breast tissue density and composition which can be interrogated optically. Modifications of development influenced by micronutrients and hormonal status from exposures (e.g. toxins), lifestyle and diet effects, may ultimately be tracked. Preliminary data suggests that ORS has the ability to detect differences in bulk tissue properties in the developing breast of adolescent girls when compared to developmental stages assessed by Tanner, regional variation within breast tissue structure and asymmetries between left and right breast size and shape. Spectral comparison of unilateral breast development permits adjusting the optode separation as function of developmental breast size to minimize optical sampling of pectoral muscle.

Paper Details

Date Published: 12 October 2005
PDF: 7 pages
Proc. SPIE 5970, Photonic Applications in Devices and Communication Systems, 59701F (12 October 2005); doi: 10.1117/12.628512
Show Author Affiliations
Samantha N. Dick, Ontario Cancer Institute, Univ. Health Network (Canada)
Lothar Lilge, Ontario Cancer Institute, Univ. Health Network (Canada)
Univ. of Toronto (Canada)

Published in SPIE Proceedings Vol. 5970:
Photonic Applications in Devices and Communication Systems
Peter Mascher; John C. Cartledge; Andrew Peter Knights; David V. Plant, Editor(s)

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