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Proceedings Paper

Artificial bilayer lipid membranes (BLMs) on-chip for single molecule sensing
Author(s): Mairi E. Sandison; Daniele Malleo; David Holmes; Richard Berry; Hywel Morgan
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Paper Abstract

A polymer microfluidic device for the formation of artificial bilayer lipid membranes (BLMs) on-chip is described. The device is fabricated from thin, transparent films of poly(methyl methacrylate), allowing for optical monitoring of the BLM. In addition, detection of single fluorescently-labeled lipid molecules using conventional epifluorescence microscopy is described.

Paper Details

Date Published: 28 June 2005
PDF: 6 pages
Proc. SPIE 5838, Nanotechnology II, (28 June 2005); doi: 10.1117/12.608645
Show Author Affiliations
Mairi E. Sandison, Univ. of Southampton (United Kingdom)
Daniele Malleo, Univ. of Southampton (United Kingdom)
David Holmes, Univ. of Southampton (United Kingdom)
Richard Berry, Univ. of Oxford (United Kingdom)
Hywel Morgan, Univ. of Southampton (United Kingdom)

Published in SPIE Proceedings Vol. 5838:
Nanotechnology II
Paolo Lugli; Laszlo B. Kish; Javier Mateos, Editor(s)

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