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Proceedings Paper

Multichannel fiber system for luminescence diagnostics of tumors
Author(s): Victor B. Loschenov; M. V. Baryshev; Natalia N. Zharkova; Vjacheslav G. Artioushenko; Alexander Krjukov; Alexander Startsev; Kelly B. Moran; Joseph D. Brown
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Paper Abstract

Fiber-optic catheters currently in use make it impossible to solve the main problem of spectral fluorescence diagnostics and to provide the high accuracy and reproducibility of in vivo tissue fluorescence investigations. It is well known that fluorescence signal intensity is varied with distance and angle between the biological tissue and the distal tip of the catheter. Signal intensity also depends on the arrangement of light delivery fibers relative to light collecting fibers. Taking these things into account, we developed a design for catheters which allows them to perform the endoscopical diagnostics of tumors with substantial reduction of confusing influences. The new catheters have been tested in preclinical and clinical practice. Their design fits the requirements of certain diagnostic aims, but could also be specified for other applications: measurements of reflection and scattering characteristics of the object, plasma emission spectra (during lithotripsy or angioplasty), etc. There also are wide areas of possible applications for spectra measurements of gaseous, liquid, or solid substances in biology and chemistry.

Paper Details

Date Published: 1 August 1992
PDF: 4 pages
Proc. SPIE 1649, Optical Fibers in Medicine VII, (1 August 1992); doi: 10.1117/12.60232
Show Author Affiliations
Victor B. Loschenov, General Physics Institute (Russia)
M. V. Baryshev, General Physics Institute (Russia)
Natalia N. Zharkova, General Physics Institute (Russia)
Vjacheslav G. Artioushenko, CeramOptec Systems (Russia)
Alexander Krjukov, CeramOptec Systems (Russia)
Alexander Startsev, CeramOptec Systems (Russia)
Kelly B. Moran, CeramOptec Inc. (United States)
Joseph D. Brown, CeramOptec Inc. (United States)

Published in SPIE Proceedings Vol. 1649:
Optical Fibers in Medicine VII
Abraham Katzir, Editor(s)

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