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Proceedings Paper

Visualization and quantitative analysis of lung microstructure using micro CT images
Author(s): Tetsuo Yamamoto; Mitsuru Kubo; Yoshiki Kawata; Noboru Niki; Masashi Fujii; Yoshihiro Nakaya; Eisuke Matsui; Hironobu Ohmatsu; Noriyuki Moriyama
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Paper Abstract

Micro CT system is developed for lung function analysis at a high resolution of the micrometer order (up to 5μm in spatial resolution). This system reveals the lung distal structures such as interlobular septa, terminal bronchiole, respiratory bronchiole, alveolar duct, and alveolus. In order to visualize lung 3-D microstructures using micro CT images and to analyze them, this research presents a computerized approach. This approach is applied for to micro CT images of human lung tissue specimens that were obtained by surgical excision and were kept in the state of the inflated fixed lung. This report states a wall area such as bronchus wall and alveolus wall about the extraction technique by using the surface thinning process to analyze the lung microstructures from micro CT images measured by the new-model micro CT system.

Paper Details

Date Published: 14 April 2005
PDF: 8 pages
Proc. SPIE 5746, Medical Imaging 2005: Physiology, Function, and Structure from Medical Images, (14 April 2005); doi: 10.1117/12.595043
Show Author Affiliations
Tetsuo Yamamoto, Univ. of Tokushima (Japan)
Mitsuru Kubo, Univ. of Tokushima (Japan)
Yoshiki Kawata, Univ. of Tokushima (Japan)
Noboru Niki, Univ. of Tokushima (Japan)
Masashi Fujii, Toshiba IT & Control Systems (Japan)
Yoshihiro Nakaya, National Cancer Ctr. Hospital East Radiology Division (Japan)
Eisuke Matsui, Gifu Environmental Medicine Research Institute (Japan)
Hironobu Ohmatsu, National Cancer Ctr. Hospital East (Japan)
Noriyuki Moriyama, National Cancer Ctr. Research Ctr. for Cancer Prevention and Screening (Japan)

Published in SPIE Proceedings Vol. 5746:
Medical Imaging 2005: Physiology, Function, and Structure from Medical Images
Amir A. Amini; Armando Manduca, Editor(s)

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