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Proceedings Paper

Terahertz spectroscopic characterization of cancer cells
Author(s): Tatiana Globus; Dan Theodorescu M.D.; Henry Frierson M.D.; Tatyana Khromova; Dwight Woolard
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Paper Abstract

This work presents the first demonstration of the characterization of cancer cells using Fourier Transform Infrared Spectroscopy (FTIR) technique in the low terahertz frequency range of 10-25 cm-1 and shows how this technique can be used to discriminate between two types of cancer (prostate and bladder) in cell culture. Samples of cancer cells suspended in buffer solution with the ratio of dry material to liquid ~ 1:10 were prepared and measured. The work will serve as the foundation for future work defining specific spectra associated with different tumor histologies and tumor progression and metastasis.

Paper Details

Date Published: 1 April 2005
PDF: 8 pages
Proc. SPIE 5692, Advanced Biomedical and Clinical Diagnostic Systems III, (1 April 2005); doi: 10.1117/12.594391
Show Author Affiliations
Tatiana Globus, Univ. of Virginia (United States)
Dan Theodorescu M.D., Univ. of Virginia (United States)
Henry Frierson M.D., Univ. of Virginia Medical Ctr. (United States)
Tatyana Khromova, Univ. of Virginia (United States)
Dwight Woolard, U.S. Army Research Lab. (United States)

Published in SPIE Proceedings Vol. 5692:
Advanced Biomedical and Clinical Diagnostic Systems III
Tuan Vo-Dinh; Warren S. Grundfest M.D.; David A. Benaron M.D.; Gerald E. Cohn, Editor(s)

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