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Proceedings Paper

Spectroscopic Fourier domain optical coherence tomography: principle, limitations, and applications
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Paper Abstract

Fourier Domain Optical Coherence Tomography (FD OCT) recently gained large reputation as a high speed imaging modality with increased sensitivity. Since the spectrum of the backscattered light is directly available, the method is a natural candidate for performing spectroscopic tissue analysis. Spectroscopic data is extracted by applying a windowed Fourier transform. The precision of the method is analyzed by measuring the absorbance of ICG samples sandwiched between microscope glass plates. A Ti:Sapph laser serves as light source with a spectral bandwidth of 160nm. For spectral analysis of tissue two distinct spectral regions are selected by multiplying the FD OCT signal spectrum with appropriate Gaussian window functions. One obtains two tomograms that enhance slightly different structures. Finally light sources of different spectral widths are synthesized and the resulting OCT tomograms that exhibit different axial resolutions are compared with respect to image quality and structure recognition.

Paper Details

Date Published: 13 April 2005
PDF: 8 pages
Proc. SPIE 5690, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine IX, (13 April 2005); doi: 10.1117/12.592911
Show Author Affiliations
Rainer Andreas Leitgeb, Medical Univ. of Vienna (Austria)
Ecole Polytechnique Federale de Lausanne (Switzerland)
Wolfgang Drexler, Medical Univ. of Vienna (Austria)
Boris Povazay, Medical Univ. of Vienna (Austria)
Boris Hermann, Medical Univ. of Vienna (Austria)
Harald Sattmann, Medical Univ. of Vienna (Austria)
Adolf Friedrich Fercher, Medical Univ. of Vienna (Austria)

Published in SPIE Proceedings Vol. 5690:
Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine IX
Valery V. Tuchin; Joseph A. Izatt; James G. Fujimoto, Editor(s)

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