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Proceedings Paper

Ultrahigh-resolution polarization-sensitive optical coherence tomography
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Paper Abstract

We present, to the best of our knowledge, the first ultrahigh resolution, polarization sensitive OCT images of human tissue in vivo. The system is based on a Mach Zehnder interferometer and a transversal scanning of the sample. A broadband superluminescent diode with a center wavelength of 897nm and a bandwidth (FWHM) of 155nm was used. The depth resolution of the system was measured with ~ 4 micrometer in air. The actual scanning speed of 1000 transversal lines per second enables the acquisition of an image (B-scan) consisting of 1600(x) x 1000(z) pixels in 1 second. The whole signal is recorded by a polarization sensitive detection unit at the interferometer exit which enables a phase resolved measurement. From the recorded data we were able to obtain backscattered intensity, retardation and cumulative fast axis orientation of the sample. Images of these parameters obtained from a technical sample and from a human cornea in vivo are presented.

Paper Details

Date Published: 13 April 2005
PDF: 6 pages
Proc. SPIE 5690, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine IX, (13 April 2005); doi: 10.1117/12.592700
Show Author Affiliations
Michael Pircher, Medical Univ. of Vienna (Austria)
Erich Goetzinger, Medical Univ. of Vienna (Austria)
Rainer Andreas Leitgeb, Medical Univ. of Vienna (Austria)
Ecole Polytechnique Federale de Lausanne (Switzerland)
Harald Sattmann, Medical Univ. of Vienna (Austria)
Christoph K. Hitzenberger, Medical Univ. of Vienna (Austria)

Published in SPIE Proceedings Vol. 5690:
Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine IX
Valery V. Tuchin; Joseph A. Izatt; James G. Fujimoto, Editor(s)

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