Share Email Print

Proceedings Paper

Novel cantilever for biosensing applications
Author(s): Omkar G. Karhade; Sudhir S. Chiluveru; Prakash R. Apte
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

Chemomechanical actuation of a microcantilever beam induced by biomolecular binding such as DNA hybridization and antibody-antigen binding is an important principle useful in biosensing applications. As the magnitude of the forces involved is very small, increasing the sensitivity of the microcantilever beams involved is a priority. In this paper we are considering to achieve this by structural variation of the cantilevers. Merely decreasing the thickness of the microcantilever may improve the sensitivity, but it gives rise to the disadvantages of 'arching' and lesser reliability due to greater probability of defects during fabrication. We consider a 'ribbed' cantilever that eliminates the disadvantages while improving the sensitivity simultaneously. Simulations for validation have been performed using the finite element analysis software ANSYS 8.0. The simulations reveal that a ribbed microcantilever is almost as sensitive as a thin cantilever and has relatively very low arching effect. Simulations also reveal that higher the arching lower is the sensitivity.

Paper Details

Date Published: 22 January 2005
PDF: 6 pages
Proc. SPIE 5718, Microfluidics, BioMEMS, and Medical Microsystems III, (22 January 2005); doi: 10.1117/12.589679
Show Author Affiliations
Omkar G. Karhade, Indian Institute of Technology/Bombay (India)
Sudhir S. Chiluveru, Indian Institute of Technology/Bombay (India)
Prakash R. Apte, Indian Institute of Technology/Bombay (India)

Published in SPIE Proceedings Vol. 5718:
Microfluidics, BioMEMS, and Medical Microsystems III
Ian Papautsky; Isabelle Chartier, Editor(s)

© SPIE. Terms of Use
Back to Top
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?