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Proceedings Paper

Human expiration content diagnostics by tunable diode lasers in middle infrared
Author(s): Andrian I. Kouznetsov; Konstantin L. Moskalenko; Alexander I. Nadezhdinskii; Eugene V. Stepanov
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Paper Abstract

Results on the application of tunable diode laser gas analysis to determining the trace components of human breath are presented. Schemes of the analyzers specially developed for measurement of both carbon oxides in expiration are described. A few results illuminating possible applications of TDL in high sensitive medical diagnostics have been obtained. For nonsmokers, the expired concentration of CO is slightly higher than inhaled air. Specific surplus value depends on the person's age. The surplus CO content increased significantly just after intensive physical exercises like jogging. For smokers, the farmacokinetical curve of abundant CO removal from the organism could be investigated. The smoking status of tested individuals becomes easy available. Breath-hold simultaneous measurements of CO and CO2 have shown the difference in the dependencies of their concentrations on breath-holding time. The possibility to investigate phenomena like molecular pulmonary diffusion of the alveolar-capillary membrane and an organism's compensation reactions to oxygen shortage seems to become real. Perspective leads for development and the application of diode laser spectroscopy methods to the analysis of gaseous microimpurities in medicine are also discussed.

Paper Details

Date Published: 1 April 1992
PDF: 18 pages
Proc. SPIE 1724, Tunable Diode Laser Applications, (1 April 1992); doi: 10.1117/12.58677
Show Author Affiliations
Andrian I. Kouznetsov, General Physics Institute (Russia)
Konstantin L. Moskalenko, General Physics Institute (Russia)
Alexander I. Nadezhdinskii, General Physics Institute (Russia)
Eugene V. Stepanov, General Physics Institute (Russia)

Published in SPIE Proceedings Vol. 1724:
Tunable Diode Laser Applications
Alexander I. Nadezhdinskii; Alexander M. Prokhorov, Editor(s)

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