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Proceedings Paper

Experimental study using ER-YAG laser in discs: changes in glycosaminoglycan content and synthesis in discs
Author(s): Kazuyuki Maehara M.D.; Sadaaki Nakai M.D.; Kumi Naga M.D.; Seiji Nishimoto M.D.
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Paper Abstract

Changes in discs after Er-Yag laser irradiation are scarcely reported. We made an experimental study using white rabbits and Er-Yag laser. Under general anesthesia, Er-Yag laser was irradiated into lumbar discs. Three or 8 weeks after irradiation, rabbits were sacrificed, and these discs were extracted. The quantitative analysis of the glycosaminoglycan content in the annulus fibrosus, and the incorporation of 35S-sulfate in chondroitin 4 sulfate were measured. The results showed, the increased incorporation of 35S-sulfate in chondroitin 4 sulfate and chondroitin 6 sulfates in groups of laser irradiation may indicate Er-Yag laser irradiation in nucleus pulposus, accelerated glycosaminoglycan production, in the annulus fibrosus. But no difference of unsaturated isomers of chondroitin 4 sulfate, and chondroitin 6 sulfate, and no difference of saturated isomer of keratan sulfate indicate, the influence of Er-Yag laser irradiation was not so high, as to bring the quantitative changes of matrix of annulus fibrosus in term of 8 weeks.

Paper Details

Date Published: 10 September 2004
PDF: 5 pages
Proc. SPIE 5610, Laser Florence 2003: A Window on the Laser Medicine World, (10 September 2004); doi: 10.1117/12.584329
Show Author Affiliations
Kazuyuki Maehara M.D., Fujita Health Univ. (Japan)
Sadaaki Nakai M.D., Fujita Health Univ. (Japan)
Kumi Naga M.D., Fujita Health Univ. (Japan)
Seiji Nishimoto M.D., Fujita Health Univ. (Japan)

Published in SPIE Proceedings Vol. 5610:
Laser Florence 2003: A Window on the Laser Medicine World
Leonardo Longo; Alfons G. Hofstetter; Mihail-Lucian Pascu; Wilhelm R. A. Waidelich, Editor(s)

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