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Proceedings Paper

Optical detection of electrokinetically manipulated single molecules in a nanofluidic chip
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Paper Abstract

We report on the progress of a novel nanofluidic device for detecting and manipulating single molecules in solution. This paper discusses the development of an earlier proposed molecule separation method, where electrokinetic forces separate different molecules based on their masses and charges. Optical imaging using confocal microscopy is applied to perform the detection of the single molecules. Potential applications of this device will be assessed. This research aims for the high spatial and spectral resolutions, both in manipulation and detection, which can lead to molecular identification.

Paper Details

Date Published: 22 January 2005
PDF: 9 pages
Proc. SPIE 5718, Microfluidics, BioMEMS, and Medical Microsystems III, (22 January 2005); doi: 10.1117/12.583566
Show Author Affiliations
Gea O. F. Parikesit, Technische Univ. Delft (Netherlands)
Vladimir G. Kutchoukov, Technische Univ. Delft (Netherlands)
Andre Bossche, Technische Univ. Delft (Netherlands)
Ian Theodor Young, Technische Univ. Delft (Netherlands)
Yuval Garini, Technische Univ. Delft (Netherlands)

Published in SPIE Proceedings Vol. 5718:
Microfluidics, BioMEMS, and Medical Microsystems III
Ian Papautsky; Isabelle Chartier, Editor(s)

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